Myeloid Progenitor Dysregulation Drives Immunosuppressive Macrophages In Tumors
1 / 5 2 / 5 3 / 5 4 / 5 5 / 5 ❮ ❯ Myeloid Progenitor Dysregulation: The Engine of Immunosuppressive Macrophages in Cancer Cancer’s ability to evade the immune system is a significant hurdle in effective treatment. A key player in this evasion is the immunosuppressive tumor-associated macrophage (TAM). Recent research points to a crucial underlying mechanism: dysregulation of myeloid progenitors (MPs). This article delves into the complex relationship between MP dysregulation, TAM infiltration, and the resulting immunosuppressive tumor microenvironment. Understanding this process is vital for developing novel cancer immunotherapies. ...